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Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA)

Solicitation from Dept of Health and Human Services, NIH (Advanced Research Projects Agency for Health (Arpa-H)). Responses due (21 days left).

Set-aside
No set-aside stated
NAICS
541715: Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) (2022 NAICS, US Census Bureau)
Product or service code
AN13
Solicitation number
ARPA-H-SOL-26-163
Place of performance
Not stated on the notice
Posted

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Summary from the notice

Amendment 3 (11/09/2026): ISO updates to Part II - Technical Areas & Requirements: TA1: Edits to the "Target" language for the Retrospective Data Access metric. Amendment 2 (10/29/2026): Numerous changes including, but not limited to,: ISO updates in Parts I, II, III and VI; TA1 clarifications; TA2 updates; TA4 updates; Q&A link added Provides Attachment B1 for TA4 Proposal Requirements and Proposal Volume Templates. Provides Attachment A2 for TA1 Solution Summary Requirements and Attachment A3 for TA2 Solution Summary Requirements. Amendment 1 (10/14/2026): Update due dates and/or times of all TAs SPECTRA will identify and act on autism trajectories, the evolving developmental paths individuals follow across the lifespan from the prenatal period through aging, spanning autism characteristics, co-occurring conditions, and functional outcomes together with the genetic, biological, behavioral, iatrogenic (medical influences), environmental factors and their nonlinear interactions. Rather than examining these factors in isolation, SPECTRA will examine how they combine and interact, including their nonlinear interactions, to produce autism and its co-occurring conditions over time...

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